HORDB

ID: hor006511
Uniprot ID: O09163
Protein name: GnRH-associated peptide 1
Gene name: GNRH1
Organism: Mesocricetus auratus (Golden hamster)
Family: GnRH family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Mesocricetus (genus), Cricetinae (subfamily), Cricetidae (family), Muroidea, Myomorpha (suborder), Rodentia (order), Glires, Euarchontoglires (superorder), Boreoeutheria, Eutheria, Theria, Mammalia (class), Amniota, Tetrapoda, Dipnotetrapodomorpha, Sarcopterygii (superclass), Euteleostomi, Teleostomi, Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity; GO:0005183 gonadotropin hormone-releasing hormone activity
GO BP: GO:0007165 signal transduction
GO CC: GO:0005576 extracellular region; GO:0005615 extracellular space

Function: Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones.
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
Kd: NA
Half life: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor006511_AF2.pdb

hor006511_ESM.pdb

Mass:	672065	Formula:	C251H396N72O85S2
Absent amino acids:	Y	Common amino acids:	E
pI:	4.14	Basic residues:	7
Polar residues:	8	Hydrophobic residues:	15
Hydrophobicity:	-85.8	Boman Index:	-14083
Half-Life / Aliphatic Index:	1.4 hour	Aliphatic Index:	83.8
Instability Index:	8299	Extinction Coefficient cystines:	5500
Absorbance 280nm:	112.24